Prevalence of abnormal findings in 230 knees of asymptomatic adults using 3.0 T MRI
Our take
If my knee MRI shows abnormalities, does that mean something is wrong with my knee?
In adults with no knee symptoms, MRI abnormalities are almost universal, so an abnormal scan on its own does not explain pain and must be interpreted alongside the clinical picture.
DescriptiveRead paper
Primary study115 ParticipantsModerate evidence
Key points
- Nearly all asymptomatic knees scanned showed at least one MRI abnormality
- Meniscal tears, cartilage damage, and bone marrow changes were common despite no symptoms
- Even findings usually considered serious, like bucket-handle and complex meniscal tears, appeared in pain-free knees
- Imaging findings poorly predict symptoms, so MRI results need clinical correlation
How it was conducted
- Design
- Cross-sectional prevalence study using 3.0 T MRI
- Participants
- 115 uninjured sedentary adults, median age 44, both knees imaged (230 knees)
- Imaging
- Bilateral 3.0 T knee MRI graded by two radiologists
- Symptom measure
- KOOS knee questionnaires to confirm asymptomatic status
- Outcome
- Prevalence of structure-specific abnormalities across all knees
What they found
- Abnormalities were present in 97% of knees
- Meniscal tears occurred in 30% of knees, with horizontal tears the most common at 23%
- Patellofemoral cartilage abnormalities were found in 57% of knees and bone marrow abnormalities in 48%
- Moderate cartilage lesions occurred in 19% of knees and severe lesions in 31%
- Moderate bone marrow edema occurred in 19% of knees and severe in 31%
- Partial ACL ruptures were seen in 2% of knees
- Bucket-handle and complex meniscal tears were reported in asymptomatic knees
Limitations
- Cross-sectional design shows prevalence at one time point and cannot prove findings cause or predict symptoms
- Participants were sedentary adults with a median age of 44, so results may not transfer to athletes or other age groups
- No symptomatic comparison group is described, limiting conclusions about how these findings differ from painful knees
- Radiologist grading of structures can carry interpretation variability
Why it matters
- For patients
- An abnormal knee MRI does not by itself mean your pain has been explained, since many pain-free people have the same findings.
- For clinicians
- Knee MRI findings should be interpreted in the context of symptoms and examination rather than treated as the cause of pain on their own.
- For readers
- This study shows how common incidental MRI abnormalities are in healthy knees, a key caution against over-relying on imaging.
Source
doi:10.1007/s00256-020-03394-z
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